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MYP_035627
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Basic Information
Antimicrobial peptide Xac-1 (Xylopin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
17 amino acids
C96H162N24O18
Standard
Sequence
GFVALLKKLPLILKHLH
Physicochemical Analysis
1940.46 Da
10.30
2.93
2.62
0.1724
0.94
0.55
0.35
17.09
183.53
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
655.55
0.85
22.0
23.0
65.0
138.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273444 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
25 μM
IC50
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
RECORD: Rec_0303740 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus agalactiae (CS)
3.75 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
RECORD: Rec_0306022 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli NBRC 14237
3.1 μM
MIC
PaperIsolation of biologically active peptides from the venom of Japanese carpenter bee, Xylocopa appendiculata
RECORD: Rec_0306508 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Rat blood
100 μM
Hemolysis
PMID28546807;28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28546807/
RECORD: Rec_0307791 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella boydii (CS)
3.75 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
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