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MYP_035627
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Basic Information
Antimicrobial peptide Xac-1 (Xylopin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
17 amino acids
C96H162N24O18
Standard
Sequence
GFVALLKKLPLILKHLH
Physicochemical Analysis
1940.46 Da
10.30
2.93
2.62
0.1724
0.94
0.55
0.35
17.09
183.53
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
655.55
0.85
22.0
23.0
65.0
138.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008244 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata circumvolans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Gram Negative Bacteria and Gram Positive Bacteria
PMID28546807;28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28546807/
RECORD: Rec_0020342 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus (ATCC 10240)
1.9 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
RECORD: Rec_0049045 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata circumvolans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus ATCC 10240
1.9 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
RECORD: Rec_0050380 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Stenotrophomonas maltophilia (ATCC 13637)
3.75 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
RECORD: Rec_0054533 VERIFIED: YES
Provenance & Taxonomy
Xylocopa appendiculata circumvolans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3.75 μM
MIC
PMID28855917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28855917/
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