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MYP_035621
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Basic Information
Temporin-HN1 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C77H124N20O18
Standard
Sequence
AILTTLANWARKFL
Physicochemical Analysis
1617.93 Da
11.00
1.79
1.61
0.1282
0.71
0.64
0.25
4.90
132.86
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
628.88
-3.06
23.0
20.0
51.0
115.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0276457 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. carnosus KHS
37.5 μM
MIC
PaperNovel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis.
RECORD: Rec_0293117 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
washed human erythrocytes
75 μM
IC50
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0305201 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus carnosus KHS
37.5 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0308273 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC2002
75 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0309434 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Hemolytic activity against human erythrocytes
75 μM
LC50
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
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