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MYP_035621
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Basic Information
Temporin-HN1 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C77H124N20O18
Standard
Sequence
AILTTLANWARKFL
Physicochemical Analysis
1617.93 Da
11.00
1.79
1.61
0.1282
0.71
0.64
0.25
4.90
132.86
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
628.88
-3.06
23.0
20.0
51.0
115.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093365 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 64.3%, E 0.0%, T 7.1%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0145499 VERIFIED: YES
Provenance & Taxonomy
Odorrana tiannanensis [Animal]
Tiannanensin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperW. He et al. / Biochimie (2011) in press. Host defense peptides in skin secretions of Odorrana tiannanensis: Proof for other survival strategy of the frog than merely anti-microbial
RECORD: Rec_0175308 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 981
150 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0192788 VERIFIED: YES
Provenance & Taxonomy
Odorrana tiannanensis [Animal]
Tiannanensin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
46.0 μM
MIC
PaperW. He et al. / Biochimie (2011) in press. Host defense peptides in skin secretions of Odorrana tiannanensis: Proof for other survival strategy of the frog than merely anti-microbial
RECORD: Rec_0206223 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Slime mould 090223
19 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
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