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MYP_035603
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Basic Information
X. amieti-AM4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
17 amino acids
C74H134N22O20
Standard
Sequence
GLGSLVGNALRIGAKLL
Physicochemical Analysis
1651.99 Da
11.00
1.76
1.55
0.1035
1.00
0.62
0.35
0.76
166.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
680.16
-6.09
24.0
22.0
57.0
116.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053469 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21199684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21199684/
RECORD: Rec_0057898 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0066367 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
25.0 μM
MIC
PaperJ.M. Conlon et al. / Peptides 31 (2010) 989-994. Orthologs of magainin, PGLa, procaerulein-derived, and proxenopsin-derived peptides from skin secretions of the octoploid frog Xenopus amieti (Pipidae)
RECORD: Rec_0151663 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID20226221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20226221/
RECORD: Rec_0232668 VERIFIED: YES
Provenance & Taxonomy
Xenopus amieti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID20226221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20226221/
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