Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC752H1234N218O218S14

DescriptionStandard

        MLLCVTACDSLLATIPRRQIKTGVQSPTAEALKAQICISFAKTMKSLLLTLTACVVLFQTFSVCRGRKSCWVIKGHCRKNCKSGEHVKQPCKNGNYCCTPSKADPQPHGAPPAPTRKAQSFHDNMKNVKNFPVVLSINDNNVEDQLLSTSVSLPTLVH
    

Molecular Weight17266.08 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)11.83

Net Charge (pH 7.4) 11.17

Charge Density (pH 7.0) 0.0748

GRAVY Index-0.13

Hydrophobic Moment 0.58

Boman Index-0.00

Instability Index41.59

Aliphatic Index 82.66

Aromaticity 0.0443

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6987.11

LogP -79.39

H-bond Donors 248.0

H-bond Acceptors 249.0

Rotatable Bonds 569.0

Heavy Atoms 1202.0

Ring Count 24.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289141 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence