Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC365H590N100O90S8

DescriptionStandard

        GASVLLTVCLILFLLAVKSGANAFIRRFFNTCWRTKGICRKSCHKSEIFHVFCDVSILCCIDKKHLPSMVGK
    

Molecular Weight8075.73 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)7.95

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.1104

GRAVY Index0.59

Hydrophobic Moment 0.86

Boman Index0.16

Instability Index45.02

Aliphatic Index 105.56

Aromaticity 0.0972

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3032.35

LogP -23.53

H-bond Donors 116.0

H-bond Acceptors 109.0

Rotatable Bonds 270.0

Heavy Atoms 563.0

Ring Count 12.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301708 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0338372 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin