Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC466H741N131O138S12

DescriptionStandard

        YPRNDITNFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEVKRVLVNDVKLVNHTDCHCSTCYYHKS
    

Molecular Weight10771.44 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)5.92

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0624

GRAVY Index-0.41

Hydrophobic Moment 0.67

Boman Index-0.09

Instability Index51.17

Aliphatic Index 61.47

Aromaticity 0.0842

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4347.08

LogP -47.13

H-bond Donors 159.0

H-bond Acceptors 159.0

Rotatable Bonds 352.0

Heavy Atoms 747.0

Ring Count 17.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330669 VERIFIED: YES

Provenance & Taxonomy

OrganismHypophthalmichthys molitrix [Animal]

FamilyGlycoprotein hormones

Tax ID13095

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-85; 36-87; 63-90

Other Mods56:N-linked (GlcNAc...) asparagine; 81:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min