Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2576H4006N646O747S14

DescriptionStandard

        MRIKMVQVLWGCALLWNVYISSAQTVYPGIKARATQRALDYGVQAGMEVIEQIAKERNIPDLKGSESLEFLKIDYVNYNFSNIKINTFSFPNTSLAFVPGVGIKALTNHGTANISTNWEVKSPLFQDTGGADLFLSGVYFTGILVLDQNEVGHPTLKLQECHAQVSHAHVSFSGELSVLYNSFIEPIEKPILKNLNEMLCPILIGEVEALNANLSMLEVLTKIDNYTLLDYSLTSSPEITENYIDLNLKGVFYPLNNITDPPFPPVPFELPARSDSMLYIGISEYFFNSASFAHFTAGAFNVSLSTKEISSHLFRNSQGIGNMLSRIADIYILSQPFMFRIMATEPPVVSLLPGNFTLDIPASIVILTESENSTAETIVSMDFVASTSVGLVILGQRLVCSLSLNRFHLSLPESKRSNIEVLRFENVLSSILHFGVLPLANAKLQQGFPLPNPYKISFVNSNIEVLEHFLLISTDLKYETSLKQPSRFYGWEGLNLINEQWRGKSVP
    

Molecular Weight56426.15 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-12.60

Net Charge (pH 7.4) -13.50

Charge Density (pH 7.0) -0.0248

GRAVY Index0.13

Hydrophobic Moment 0.67

Boman Index0.17

Instability Index42.47

Aliphatic Index 104.58

Aromaticity 0.1026

Extinction Coeff. Reduced 52830.00

Extinction Coeff. Oxidized 53080.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0161879 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllostomus discolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria