MYP_035377
Unstapled heptapeptide 3
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Standard
7 amino acids
C67H76N14O8
Standard
WWKWWWK
1205.41 Da
10.00
1.76
1.55
0.2512
-1.76
0.63
0.15
8.57
0.00
0.7143
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
368.91
5.19
15.0
10.0
31.0
89.0
10.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0148877
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Methicillin-resistant Staphylococcus aureus (MRSA)
62±10 μg/mL
MIC
RECORD: Rec_0158387
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Staphylococcus aureus ATCC25923
76±14 μg/mL
MIC
RECORD: Rec_0331773
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
The Ⓧ (position: 2 and 6) in sequence indicate (S)-4-pentenyl alanine. Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling through an oct-4-enyl hydrocarbon staple
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus ATCC 25923
8.3±1.8 μg/mL
MIC