Peptide Database

Peptide NamePi-Stichotoxin-Hcr5b

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC208H301N49O51S7

DescriptionStandard

        GTPCKCHGYIGVYWFMLAGCPNGYGYNLSCPYFLGICCVKK
    

Molecular Weight4528.37 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0678

GRAVY Index0.36

Hydrophobic Moment 0.21

Boman Index0.31

Instability Index7.69

Aliphatic Index 64.15

Aromaticity 0.1951

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1551.27

LogP -9.95

H-bond Donors 59.0

H-bond Acceptors 62.0

Rotatable Bonds 135.0

Heavy Atoms 315.0

Ring Count 13.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0303829 VERIFIED: YES

Provenance & Taxonomy

OrganismHeteractis crispa [Animal]

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-37; 6-30; 20-38

Bio-Activity Profile

Function

Toxin Channel blocker

Targetrat ASIC1a

Activity4.8 μM

MethodIC50

RECORD: Rec_0339917 VERIFIED: YES