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MYP_035314
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Basic Information
Diketopiperazine (prewp)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XP
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0178071 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial Anticancer
A2780
93.1 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0179288 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
x=Prenylated-D-Trp
Bio-Activity Profile
Antimicrobial Anticancer
A2780-cisR
85.6 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0194087 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial Anticancer
A2780-cisR
85.6 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0200064 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: A2780
100 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
RECORD: Rec_0209819 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial Anticancer
A2780
82.8 μM
IC50
PMID22617493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22617493/
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