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MYP_035252
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Basic Information
P15 (deer beta-defensin; ruminant, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
30 amino acids
C150H247N49O37S5
Standard
Sequence
IRNSLTCRFNFGICLPKRCPGRMRQIGTCF
Physicochemical Analysis
3489.20 Da
10.71
5.72
5.46
0.1906
-0.07
0.54
-0.12
37.14
65.00
0.1000
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1415.12
-14.99
55.0
48.0
114.0
241.0
5.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086064 VERIFIED: YES
Provenance & Taxonomy
Cervus elaphus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus NCTC 4163
1 μg/mL
MIC
PMID16011891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16011891/
RECORD: Rec_0140789 VERIFIED: YES
Provenance & Taxonomy
Zealand deer [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperIsolation and characterisation of antimicrobial peptides from deer neutrophils.
RECORD: Rec_0143438 VERIFIED: YES
Provenance & Taxonomy
Cervus elaphus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli O111
0.3 μg/mL
MIC
PMID16011891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16011891/
RECORD: Rec_0169697 VERIFIED: YES
Provenance & Taxonomy
Cervus elaphus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans 3135A
3 μg/mL
MIC
PMID16011891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16011891/
RECORD: Rec_0206089 VERIFIED: YES
Provenance & Taxonomy
Muntiacus muntjak [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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