Peptide Database

Peptide Namekappa-Conotoxin Ac4.3a

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC160H271N47O53S8

DescriptionStandard

        QKELVVTATTTCCGYNPMTSCPRCMCDSSCNKKKKP
    

Molecular Weight3957.67 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.1027

GRAVY Index-0.59

Hydrophobic Moment 0.45

Boman Index-0.19

Instability Index52.27

Aliphatic Index 29.72

Aromaticity 0.0278

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1633.39

LogP -22.93

H-bond Donors 62.0

H-bond Acceptors 65.0

Rotatable Bonds 130.0

Heavy Atoms 268.0

Ring Count 4.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154167 VERIFIED: NO

Provenance & Taxonomy

OrganismConus achatinus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide12-24; 13-26; 21-30

Bio-Activity Profile

Function

Toxin