Peptide Database

Peptide NameDQ2-Glia-alpha1 epitope (p58p72; S64, S69 and E65)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H119N19O25

DescriptionStandard

        LQPFPQSELPYSQPQ
    

Molecular Weight1758.92 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0825

GRAVY Index-1.09

Hydrophobic Moment 0.21

Boman Index-0.03

Instability Index175.92

Aliphatic Index 52.00

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 705.91

LogP -6.60

H-bond Donors 20.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 125.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072244 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: S64,S69; Reported substitutions/positions: E65

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay