Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC551H882N146O167S4

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLMIGNASLTVNMNWDIRTWMFKDSGRSTVYISKVLVTAIFSTPLDNTGHTSISLTSCRTTPGDIDIKLNGKS
    

Molecular Weight12352.04 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.02

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index10.47

Aliphatic Index 93.16

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5007.85

LogP -54.91

H-bond Donors 179.0

H-bond Acceptors 176.0

Rotatable Bonds 406.0

Heavy Atoms 868.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280676 VERIFIED: NO

Provenance & Taxonomy

OrganismTrogon melanurus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria