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MYP_035179
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Basic Information
Brevinin-1TOa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
23 amino acids
C112H192N30O28
Standard
Sequence
GIGSILGVIAKGLPTLISWIKNR
Physicochemical Analysis
2406.91 Da
11.17
2.76
2.55
0.1199
0.77
0.55
0.34
15.24
152.61
0.0435
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
928.24
-6.37
33.0
31.0
80.0
170.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031993 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
20 μM
MIC
PMID19799928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19799928/
RECORD: Rec_0118189 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi okiensis [Animal]
Brevinin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
5.0 μM
MIC
PaperJ.M. Conlon et al. / Toxicon 55 (2010) 430-435. Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies Evidence URLhttps://www.uniprot.org/uniprotkb/D5MTH2/entry
RECORD: Rec_0176407 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID19799928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19799928/
RECORD: Rec_0191593 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
5 μM
MIC
RECORD: Rec_0262811 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 39.1%, E 0.0%, T 26.1%, C 34.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
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