Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC348H565N95O87S8

DescriptionStandard

        MKLLLLTLAALLLLSQLTPGDAQKCWNLNGKCRHRCSRKESVYVYCTNGKMCCVKPKYQPKPKPWLF
    

Molecular Weight7728.31 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.15

Charge Density (pH 7.0) 0.1421

GRAVY Index-0.21

Hydrophobic Moment 0.40

Boman Index-0.03

Instability Index23.03

Aliphatic Index 87.31

Aromaticity 0.0896

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2935.32

LogP -22.18

H-bond Donors 107.0

H-bond Acceptors 106.0

Rotatable Bonds 255.0

Heavy Atoms 538.0

Ring Count 14.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0158945 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10036

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic