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MYP_035161
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Basic Information
Caerin 1.6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C124H205N31O29
Standard
Sequence
GLFSVLGAVAKHVLPHVVPVIAEKL
Physicochemical Analysis
2594.14 Da
8.61
0.94
0.63
0.0374
1.22
0.43
0.47
25.92
159.60
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
911.07
-3.18
30.0
32.0
81.0
184.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161831 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus uberis
25 μg/mL
MIC
PMID10601876 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10601876/
RECORD: Rec_0172305 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Litoria xanthomera [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Micrococcus luteus
25 μg/mL
MIC
PaperNew caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera.
RECORD: Rec_0206563 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermis
12 μg/mL
MIC
PMID10601876 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10601876/
RECORD: Rec_0225976 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Litoria xanthomera [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
P. haemolytica
50 μg/mL
MIC
PaperNew caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera.
RECORD: Rec_0226771 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Litoria xanthomera [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Bacillus cereus
100 μg/mL
MIC
PaperNew caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera.
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