Peptide Database

Peptide Namehepcidin TH1-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC86H146N28O23S8

DescriptionStandard

        GIKCRFCCGCCTPGICGICCR
    

Molecular Weight2196.77 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.1276

GRAVY Index0.93

Hydrophobic Moment 0.32

Boman Index0.15

Instability Index8.88

Aliphatic Index 55.71

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 806.58

LogP -10.02

H-bond Donors 37.0

H-bond Acceptors 34.0

Rotatable Bonds 69.0

Heavy Atoms 145.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116736 VERIFIED: YES

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)