Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2347H3695N625O658S17

DescriptionStandard

        AVQHHSAARMGAQSLAVACGALALCLTLARATNPGILVRITEAGLDYAHLQGMAILEKELTHVKLPDFSGDFRIRHVGKVHYELSGLDLQNFHLPYSRISLVPNVGLQVSISNAFADVNGNWRVKIHFLRDHGSFDITVENVYIKVNLKLGNNTSGKPTIDTSYCSTRISKVRVRFSGKLGYVTSLYRPRIGLRCISFPQICDIVAKSVRSDLQPYVQTLPVTAKIDAVAGVDYSLVGPPTATTQSLDVPMKGECYSLAQRSAVPFSPLALTLPPDHDRMVYFGVSSYFFNTASVAYHEAGALVFEITDSMIPKTIDFHLKTTTFSAFVPQVKKYPDMQMKLRLSAPSAPFLNIGPGGLSLRPVVDIQAYAILPNASMAPLFLLSLVSLGTACSNDSGSRWAAPGAFTALADVVWLVNRLGQGFPLPLLDRIQLSDILVQFHQVSVGSPQPWPEPILFPPEPSAREAACLLLLAPC
    

Molecular Weight51740.34 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)6.86

Net Charge (pH 7.4) 5.81

Charge Density (pH 7.0) 0.0144

GRAVY Index0.19

Hydrophobic Moment 0.70

Boman Index0.15

Instability Index38.05

Aliphatic Index 101.41

Aromaticity 0.0861

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150285 VERIFIED: NO

Provenance & Taxonomy

OrganismCalidris pygmaea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria