Peptide Database

Peptide NameCalcitonin gene-related peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC160H253N49O50S3

DescriptionStandard

        ACNTATCVTHRLADFLSRSGGMAKNNFVPTNVGSAF
    

Molecular Weight3759.21 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.86

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0518

GRAVY Index0.08

Hydrophobic Moment 0.70

Boman Index0.09

Instability Index29.72

Aliphatic Index 59.72

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1602.80

LogP -22.64

H-bond Donors 58.0

H-bond Acceptors 56.0

Rotatable Bonds 119.0

Heavy Atoms 262.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064142 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyCalcitonin

Tax ID8406

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-7

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide

RECORD: Rec_0211799 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyCalcitonin gene-related peptide

Tax ID8406

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0264995 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/