Peptide Database

Peptide NamePUIB_WHEAT

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC747H1151N207O207S14

DescriptionStandard

        IRRVIQGRLGGFLGIWRGEVFKQLQRAQSLPSKCNMGADCKFPSGYYWKDYVMERCFTMKDFPVTWPTKWWKGGCEHEVREKCCKQLSQIAPQCRCDSMKTLFLLALLALVASTTFAQYSEVGGWYNEVGGGGGSQQCPQERPKLSSC
    

Molecular Weight16792.30 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.32

Charge Density (pH 7.0) 0.0524

GRAVY Index-0.36

Hydrophobic Moment 0.63

Boman Index-0.02

Instability Index45.91

Aliphatic Index 62.57

Aromaticity 0.1216

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 41075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6678.83

LogP -63.02

H-bond Donors 243.0

H-bond Acceptors 230.0

Rotatable Bonds 553.0

Heavy Atoms 1175.0

Ring Count 32.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356916 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Tax ID4565

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme