Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length433 amino acids

Chemical FormulaC2165H3405N553O629S14

DescriptionStandard

        MSLWCLLLLLALPDPTVSTNPGVKVQITQKALDNGRQIGIAYLEEKLKSVKISNISGSEDVSPIGDVEYRLSGMRITDLGLPQSSLGLVPGTGISLSIGNAFINLHGDWHVTYLGFIQDSGCFDLDISGLTIKATISVGSDETGRPSVSSNDCVARVGDANIDFHEGASWLYNLFTSFIDQLRYNKMLAMYHLVFVHLLVLATVDKYAEIEYSMVTPPSISNFLIELSLKGEFYNIGQHQEPPFSAPPFSLPPQTSSMLYIGLSSFMANSAGFVYNRARPLSLYITDDMIPSSFPMRLNTRTFGAFVPEISKRFPDMKVKILLKTSTQPKVTFEPNNVILQLIGSFTAYAILPNTTLEPLFTYKDASFSGNFWISGQNLDGSLQRYRAKISVSLSKTINQGVSLPGIGRMNLINSKLQVKKVRLLTPLNSFKT
    

Molecular Weight47693.43 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)2.02

Net Charge (pH 7.4) 1.37

Charge Density (pH 7.0) 0.0047

GRAVY Index0.08

Hydrophobic Moment 0.63

Boman Index0.14

Instability Index36.39

Aliphatic Index 99.49

Aromaticity 0.0970

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265792 VERIFIED: NO

Provenance & Taxonomy

OrganismParamormyrops kingsleyae [Bacterium]

FamilyBPI

Tax ID1676925

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence