Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC438H718N130O136S8

DescriptionStandard

        MRTLALLTAVLLVALQAQAGPLQARCDEAAGQEQRGVEDQDISISFAWDKISALQVSGSTRGLACACRLVYCRPAERRAGSCIVGGIGFTYCCSLAD
    

Molecular Weight10237.70 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-0.55

Net Charge (pH 7.4) -0.89

Charge Density (pH 7.0) -0.0057

GRAVY Index0.28

Hydrophobic Moment 0.66

Boman Index0.09

Instability Index44.14

Aliphatic Index 97.73

Aromaticity 0.0515

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4276.67

LogP -48.63

H-bond Donors 158.0

H-bond Acceptors 144.0

Rotatable Bonds 339.0

Heavy Atoms 712.0

Ring Count 8.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073409 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence