MYP_034993
Basic Information
Ala50 substitution mutant of Tat (49-57)
Anticancer
Antimicrobial
Delivery / Targeting Cell penetration Cell-penetrating peptide
Delivery / Targeting Drug delivery vehicle
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Standard
9 amino acids
C50H99N29O11
Standard
Sequence
RAKRRQRRR
Physicochemical Analysis
1282.51 Da
12.00
6.76
6.55
0.7510
-3.62
0.62
-1.88
257.44
11.11
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
736.63
-9.73
30.0
18.0
48.0
90.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0139310 VERIFIED: NO
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
RECORD: Rec_0142384 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with aminohexanoic space
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
RECORD: Rec_0147586 VERIFIED: NO
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
fluorescein with 6-aminohexanoic acid (Ahx) spacer
None
Bio-Activity Profile
Antimicrobial Anticancer
-
RECORD: Rec_0372452 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Labelled with fluorescein with aminohexanoic space
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide