Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC739H1162N218O206S12

DescriptionStandard

        MRKLSRAELKDFAFFCFERVWCQSSRMKMAHEIGFALPEIWDSIFWQNRIKASLNLGSDLDAGRICGYGTARCRRNCKRQELRVGKCPNTYPCCLKKWKVNSLNPQKDTKPRGAWLLEMATSQTSEPPFSGPSRWTVPSGSSRLVE
    

Molecular Weight16781.25 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)11.53

Net Charge (pH 7.4) 11.11

Charge Density (pH 7.0) 0.0790

GRAVY Index-0.56

Hydrophobic Moment 0.68

Boman Index-0.14

Instability Index48.64

Aliphatic Index 61.51

Aromaticity 0.1027

Extinction Coeff. Reduced 35980.00

Extinction Coeff. Oxidized 36480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6883.90

LogP -70.31

H-bond Donors 252.0

H-bond Acceptors 231.0

Rotatable Bonds 554.0

Heavy Atoms 1175.0

Ring Count 31.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101444 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin