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MYP_034952
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Basic Information
Phylloseptin-PBa3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C93H150N24O23
Standard
Sequence
FLSLIPHIVSGVAALANHL
Physicochemical Analysis
1972.33 Da
6.92
-0.07
-0.37
-0.0035
1.44
0.44
0.57
26.62
169.47
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
719.24
-4.06
24.0
25.0
60.0
140.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031167 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCPF 1467
200 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0045842 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
Candida albicans
200 μM
MIC
RECORD: Rec_0129025 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
208 μM
MIC
RECORD: Rec_0174959 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
200 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0184217 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
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