Peptide Database

Peptide NamePleurain-A2 (Pleurain A2; Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC133H220N36O38S3

DescriptionStandard

        SIITMTKEAKLPQSWKQIACRLYNTC
    

Molecular Weight3027.58 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0938

GRAVY Index-0.23

Hydrophobic Moment 0.54

Boman Index-0.03

Instability Index59.68

Aliphatic Index 82.69

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1225.73

LogP -11.37

H-bond Donors 45.0

H-bond Acceptors 44.0

Rotatable Bonds 101.0

Heavy Atoms 210.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426721 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pleuraden [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targetlittle hemolytic activity

Activity200 μg/mL

MethodHemolysis

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