‹ ›
MYP_034919
← PREVIOUS NEXT → BACK
Basic Information
Pleurain-A2 (Pleurain A2; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C133H220N36O38S3
Standard
Sequence
SIITMTKEAKLPQSWKQIACRLYNTC
Physicochemical Analysis
3027.58 Da
9.30
2.44
2.20
0.0938
-0.23
0.54
-0.03
59.68
82.69
0.0769
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1225.73
-11.37
45.0
44.0
101.0
210.0
4.0
28.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0332604 VERIFIED: YES
Provenance & Taxonomy
Rana pleuraden [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus dysenteriae
60 μg/mL
MIC
PMID17764786 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17764786/
RECORD: Rec_0341703 VERIFIED: YES
Provenance & Taxonomy
Rana pleuraden [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
20-26
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Helicobacter pylori NCTC 11637
30 μg/mL
MIC
PMID17764786 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17764786/
RECORD: Rec_0343641 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0361228 VERIFIED: YES
Provenance & Taxonomy
Nidirana pleuraden [Animal]
Pleurain
369511
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
20-26
Bio-Activity Profile
Antimicrobial Antifungal
PaperX. Wang et al. / Peptides 28 (2007) 2069-2074. A new family of antimicrobial peptides from skin secretions of Rana pleuraden Evidence URLhttps://www.uniprot.org/uniprotkb/A8B5P0/entry
RECORD: Rec_0367016 VERIFIED: YES
Provenance & Taxonomy
Rana pleuraden [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
20-26
Bio-Activity Profile
Antimicrobial Antifungal
H. pylori NCTC 11637
30 μg/mL
MIC
PaperA new family of antimicrobial peptides from skin secretions of Rana pleuraden
FIRST PREV 1 ... 3 4 5 6 7 NEXT LAST
Showing 5 records on this page · Page 5 of 7