Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length441 amino acids

Chemical FormulaC2212H3497N597O610S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGVAVLEKELAQLKLPDISGDFHIRHVGKVRYELSRLDLRSFHLPYSRISLVPNVGLQVSISNAFTELDGNWRVKIHFIRDHGSFDLKVENVYIKINLRLGNDASGKPTIATSACSTHISKVRVHFSGRFGWLYNLFYSAVESRFRTILEGKVCEIVASSVRSELQPYLQTLPVTARIDAMTGIDYSLVAPPIATARSLDAGLKGEFFSLARRSAVPFPPLALTLPPDHDRMVYFGASSYFFNTASFAYHAAGALVFEITDAMVVSPRNGGLCRCPHTLPSPLQLEKMYPNTPMKLKLSAPSAPFLNIGPEGLSLRPVVDIQAYAILPSSSLVPLFLLSLVRNVSAVINVKSGHIVGSLSVGRLKLFLTPLSAPQVRTLQSIMNIYASSILLPSLNARLDEGFPLPLPDRIQLSNILVQFHQ
    

Molecular Weight48534.71 Da

Isoelectric Point (pI)9.49

Net Charge (pH 7.0)11.61

Net Charge (pH 7.4) 10.57

Charge Density (pH 7.0) 0.0263

GRAVY Index0.16

Hydrophobic Moment 0.61

Boman Index0.13

Instability Index46.41

Aliphatic Index 106.55

Aromaticity 0.0884

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126171 VERIFIED: NO

Provenance & Taxonomy

OrganismChordeiles acutipennis (Lesser nighthawk) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria