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MYP_034872
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Basic Information
Mastoparan-C tMP-C
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C125H238N48O26
Standard
Sequence
RKKRRQRRRLNLKALLAVAKKIL
Physicochemical Analysis
2829.53 Da
12.00
10.76
10.54
0.4676
-0.89
0.58
-0.64
107.82
127.39
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1291.20
-10.58
49.0
37.0
107.0
199.0
0.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0335003 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
horse RBCs
77.94 μM
HC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0356370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Gram-positive bacteria: Staphylococcus aureus NCTC 10788
4 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0395140 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Cancer:Human squamous lung carcinoma NCI-H157
2.79 μM
IC50
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0404839 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Enterococcus faecalis NCTC 12697
16 μM
MBC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
RECORD: Rec_0412853 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Antifungal
Escherichia coli NCTC 10418
2 μM
MIC
PMID29904274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29904274/
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