Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC252H403N79O72S2

DescriptionStandard

        SSPCPPVEGPAGRQRPLCASRSRLIPAPRGAVLVQREKDLSTYNWNSFGLRY
    

Molecular Weight5755.51 Da

Isoelectric Point (pI)10.28

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0855

GRAVY Index-0.59

Hydrophobic Moment 0.52

Boman Index-0.15

Instability Index63.36

Aliphatic Index 69.42

Aromaticity 0.0769

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2427.33

LogP -27.97

H-bond Donors 87.0

H-bond Acceptors 79.0

Rotatable Bonds 178.0

Heavy Atoms 405.0

Ring Count 12.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074275 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0094626 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyKISS1

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr43 Phosphotyrosine

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0386181 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyMetastin

Tax ID10090

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Disulfide4-18

Other Mods43:Phosphotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour