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MYP_034688
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Basic Information
Ixosin (4-18)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C82H134N24O24S
Standard
Sequence
KVMREVLGYERNSYK
Physicochemical Analysis
1872.15 Da
9.52
1.76
1.55
0.1174
-1.13
0.62
-0.38
-3.81
64.67
0.1333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
824.94
-6.79
30.0
27.0
65.0
131.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038196 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0043086 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (14% Killing at 128 microM
293 μM
Hemolysis
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0061544 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa[0-10% Killing = 128 microM
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0079717 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0083371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
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