Peptide Database

Peptide NameCathelicidin-BF-15 [W3Ins;F4W;K7,13W;F8R,R9W,L11W,S14K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC124H176N34O17

DescriptionStandard

        VKWRWKKWRWKWKWKV
    

Molecular Weight2414.94 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.73

Net Charge (pH 7.4) 7.51

Charge Density (pH 7.0) 0.4830

GRAVY Index-1.84

Hydrophobic Moment 0.17

Boman Index-0.44

Instability Index73.87

Aliphatic Index 36.25

Aromaticity 0.3750

Extinction Coeff. Reduced 33000.00

Extinction Coeff. Oxidized 33000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 874.48

LogP 2.63

H-bond Donors 35.0

H-bond Acceptors 25.0

Rotatable Bonds 77.0

Heavy Atoms 175.0

Ring Count 12.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037943 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans ATCC 2002

Activity100 μg/mL

MethodMIC

RECORD: Rec_0043056 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetBacillus subtilis

Activity100 μg/mL

MethodMIC

RECORD: Rec_0082988 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus ATCC 2592

Activity100 μg/mL

MethodMIC

RECORD: Rec_0083016 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman erythrocytes

Activity11.5 μg/mL

MethodHemolysis

RECORD: Rec_0302369 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli ATCC 25922

Activity100 μg/mL

MethodMIC