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MYP_034598
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Basic Information
Witch flounder GcSc4C5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C134H196N38O32
Standard
Sequence
AGWGSIFKHIFKAGKFIHGAIQAHND
Physicochemical Analysis
2851.23 Da
9.70
2.06
1.71
0.0792
-0.06
0.70
0.23
15.78
75.38
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1114.42
-8.35
38.0
37.0
93.0
204.0
8.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0405822 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli CGSC 4908
16 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0409168 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli DC2
16 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0410656 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0413490 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis C621
16 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0416887 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa K799
32 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
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