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MYP_034598
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Basic Information
Witch flounder GcSc4C5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C134H196N38O32
Standard
Sequence
AGWGSIFKHIFKAGKFIHGAIQAHND
Physicochemical Analysis
2851.23 Da
9.70
2.06
1.71
0.0792
-0.06
0.70
0.23
15.78
75.38
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1114.42
-8.35
38.0
37.0
93.0
204.0
8.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000365 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MRSA C623
16 μg/mL
MIC
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0018704 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli CGSC 4908
16 μg/mL
MIC
PaperNovel antimicrobial peptides derived from flatfish genes. Antimicrob Agents Chemother. 2003 Aug;47(8):2464-70. doi: 10.1128/AAC.47.8.2464-2470.2003. PMID: 12878506. PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0019833 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0028287 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0034875 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21729875/ PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
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