Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC192H321N59O46S6

DescriptionStandard

        IRNPITCIKSGAICHPGFCPRRYKHIGVCGVSVIKCCKKP
    

Molecular Weight4384.36 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.47

Charge Density (pH 7.0) 0.1967

GRAVY Index0.12

Hydrophobic Moment 0.58

Boman Index0.02

Instability Index37.64

Aliphatic Index 82.75

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1660.23

LogP -15.50

H-bond Donors 64.0

H-bond Acceptors 62.0

Rotatable Bonds 141.0

Heavy Atoms 303.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415784 VERIFIED: YES

Provenance & Taxonomy

OrganismColobus angolensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)