Peptide Database

Peptide NameParathyroid hormone

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC410H677N125O127S2

DescriptionStandard

        SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFIALGAPLAPRDAGSQRPRKKEDNILVESHEKSLGEADKADVDVLTKAKSQ
    

Molecular Weight9453.65 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)0.83

Net Charge (pH 7.4) 0.39

Charge Density (pH 7.0) 0.0098

GRAVY Index-0.73

Hydrophobic Moment 0.64

Boman Index-0.18

Instability Index46.31

Aliphatic Index 89.40

Aromaticity 0.0238

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4117.90

LogP -43.04

H-bond Donors 140.0

H-bond Acceptors 134.0

Rotatable Bonds 331.0

Heavy Atoms 664.0

Ring Count 10.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050202 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyParathyroid hormone

Tax ID9541

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation ACE inhibitory

Targetosteoblastic cells

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0244876 VERIFIED: NO