Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length249 amino acids

Chemical FormulaC1277H2036N330O374S6

DescriptionStandard

        MRTNILILLQFDFYINERRSINWILRKITSLFNGFVRTHLKNQICNKLQTLLADLNTQLKTLKSKVSEYAEIDYSLRSPVVFDNSIEMGLKGVFYNTQQRVEPPSSPPAFSLASQNTNMFYIAVSAFTINSAFMVLHRTNVFNIRITDDMVPSVSPIRLSTTTFGAFIPQISETHPDLKLELKVKTVKEPIIKFEPNHVILQLLSTVTAYDVQSGNTPTQLFVLNLESVASVQVSVEEGDLALDLTLEK
    

Molecular Weight28188.20 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.13

Net Charge (pH 7.4) -0.62

Charge Density (pH 7.0) -0.0005

GRAVY Index0.03

Hydrophobic Moment 0.83

Boman Index0.09

Instability Index47.03

Aliphatic Index 105.62

Aromaticity 0.0884

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052027 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria