Peptide Database

Peptide NameMedusin-H1 (MDS-H1) (Medusin-PH) (Phyllin-PH)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC346H562N90O109S3

DescriptionStandard

        MDFLKKSLFLVLFLGFFSLSICEEEKRETEEKENEQEDDREERREEKRLLGMIPVAISAISALSKLG
    

Molecular Weight7822.90 Da

Isoelectric Point (pI)4.74

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.74

Charge Density (pH 7.0) -0.0817

GRAVY Index-0.40

Hydrophobic Moment 0.66

Boman Index-0.11

Instability Index61.62

Aliphatic Index 94.63

Aromaticity 0.0746

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3265.34

LogP -26.31

H-bond Donors 114.0

H-bond Acceptors 107.0

Rotatable Bonds 280.0

Heavy Atoms 548.0

Ring Count 6.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173184 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyFrog skin active peptide (FSAP); Medusin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-positive Cytolytic Hemolytic

TargetCandida albicans

RECORD: Rec_0407703 VERIFIED: YES