Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length505 amino acids

Chemical FormulaC2569H3986N640O740S16

DescriptionStandard

        MKMAQVLWGYFLLWNFYISSTQTIYPGIKARATQRALDYGVQAGIEMIEQMAKERNIPDLKGSESLEFLKIDYVNYNFTNIKIHALSFPNTSLAFVPGVGIKALTNHGMANISTNWEVKSPLFQDTGGADLFLSGVYFTGLLILTRNDFGHPTLQLQDCYSQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEVLTKMDNYTLLDFSLLNAPEITENNIDLDLKGVFYPLENLADPPFPSVPFVLPERSDSMLYIGISEYFFKSASFAYFTAGAFNVTLSTKEISSHLVQNSQGVGNVLSRIAEIYILSQPFMIRIMATAPPVINLLPGNFTLDIPASIVILTQPENSTVETIVSMDFVASTSVGLVILGQRLICSLSLNRFRLTLPKSSRSNIEVLRFENILSFIIHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLRYETSLKQQPSFHGWEGLNLISGQWSGNSAP
    

Molecular Weight56190.01 Da

Isoelectric Point (pI)5.20

Net Charge (pH 7.0)-13.59

Net Charge (pH 7.4) -14.47

Charge Density (pH 7.0) -0.0269

GRAVY Index0.16

Hydrophobic Moment 0.67

Boman Index0.19

Instability Index40.47

Aliphatic Index 104.26

Aromaticity 0.1050

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51465.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066596 VERIFIED: NO

Provenance & Taxonomy

OrganismRousettus aegyptiacus (Egyptian rousette) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria