Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC924H1398N208O285S6

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRQFIDLDLKGIVYPAGNYTGSPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTATEIPTISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSLALNIFDQKLVGSLCLNR
    

Molecular Weight20172.60 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0778

GRAVY Index0.29

Hydrophobic Moment 0.62

Boman Index0.24

Instability Index43.97

Aliphatic Index 94.37

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7822.43

LogP -84.34

H-bond Donors 267.0

H-bond Acceptors 277.0

Rotatable Bonds 640.0

Heavy Atoms 1423.0

Ring Count 35.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267736 VERIFIED: NO

Provenance & Taxonomy

OrganismLarus smithsonianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

RECORD: Rec_0272731 VERIFIED: NO