Peptide Database

Peptide NameGuanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length633 amino acids

Chemical FormulaC3214H5111N875O970S26

DescriptionStandard

        MESGPKMLAPICLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFIYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVDDSTEFVSFFPDFIWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNLPRECIRRFFPKRKCFIFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFSSYIFTHARTKTLREGIIVTGNRLGTLAVTYVEAVNSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKFPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQVVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSLKENIAQLKQKLQMEREQLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDITKNDDTPWIARTLDKLADELTAVLSAPAKLIGHGVKGVSSLFKKHKLPF
    

Molecular Weight72362.93 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-8.14

Net Charge (pH 7.4) -9.45

Charge Density (pH 7.0) -0.0129

GRAVY Index-0.48

Hydrophobic Moment 0.79

Boman Index-0.06

Instability Index38.38

Aliphatic Index 84.88

Aromaticity 0.0758

Extinction Coeff. Reduced 57870.00

Extinction Coeff. Oxidized 58370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0160481 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic

TargetMycobacterium bovis

RECORD: Rec_0219847 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic

TargetListeria monocytogenes

RECORD: Rec_0233710 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic

TargetToxoplasma gondii