Peptide Database

Peptide NameGlucagon-like peptide 2-I

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC155H242N44O55S

DescriptionStandard

        HAEDVNALLDRTMAKTFIEWLEKQNSNDQTD
    

Molecular Weight3633.91 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-4.14

Net Charge (pH 7.4) -4.40

Charge Density (pH 7.0) -0.1335

GRAVY Index-1.00

Hydrophobic Moment 0.61

Boman Index-0.19

Instability Index42.35

Aliphatic Index 69.35

Aromaticity 0.0645

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1652.20

LogP -18.17

H-bond Donors 55.0

H-bond Acceptors 53.0

Rotatable Bonds 124.0

Heavy Atoms 255.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192661 VERIFIED: NO

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyGlucagon

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0244548 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyGlucagon-like peptide

Tax ID7757

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0395667 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/