Peptide Database

Peptide NameBrevinin-2-AJ7 antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC355H589N91O113S6

DescriptionStandard

        MFTMKKSLLVLFFLGTISLSLCEEERNADEDDGEMTEEEKRGLVSTFKQVGISAIKGAAKNVLDVLSCKIAKTC
    

Molecular Weight8132.41 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0339

GRAVY Index0.05

Hydrophobic Moment 0.63

Boman Index0.04

Instability Index33.25

Aliphatic Index 94.86

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3318.98

LogP -31.81

H-bond Donors 118.0

H-bond Acceptors 117.0

Rotatable Bonds 288.0

Heavy Atoms 565.0

Ring Count 4.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312883 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyBrevinin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0396414 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

FamilyBrevinin

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal