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MYP_034430
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Basic Information
Antimicrobial peptide Brevinin-2GHa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
34 amino acids
C151H247N43O43S2
Standard
Sequence
GFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
Physicochemical Analysis
3416.97 Da
9.79
4.73
4.49
0.1392
0.16
0.61
0.12
16.21
77.94
0.0882
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1407.00
-16.88
50.0
50.0
117.0
239.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038350 VERIFIED: NO
Provenance & Taxonomy
Rana guentheri,Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0066294 VERIFIED: YES
Provenance & Taxonomy
Rana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus FDA209P
14.9 μg/mL
MIC
PMID16979798 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16979798/
RECORD: Rec_0193172 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus FDA209P
4.4 μM
MIC
PaperPurification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri
RECORD: Rec_0198143 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Brevinin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
PMID16621155 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16621155/
RECORD: Rec_0252797 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
4.4 μM
MIC
PaperJ. Zhou et al. / Peptides 27 (2006) 3077-3084. Purification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri Evidence URLhttps://www.uniprot.org/uniprotkb/P84860/entry
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