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MYP_034408
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Basic Information
Protonectin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C58H107N13O14
Standard
Sequence
ILGTILGLLKGL
Physicochemical Analysis
1210.55 Da
8.75
0.76
0.55
0.0633
1.85
0.38
0.66
20.04
227.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.67
-0.54
15.0
15.0
42.0
85.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156037 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. krusei ATCC 6258
16 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0159195 VERIFIED: NO
Provenance & Taxonomy
Protonectarina sylveirae [Animal]
MCD
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID7513243 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7513243/; https://www.uniprot.org/uniprotkb/P0C1R1/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0161991 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. krusei ATCC 6258
16 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0162647 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0172374 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. albicans14-2
32 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
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