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MYP_034408
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Basic Information
Protonectin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C58H107N13O14
Standard
Sequence
ILGTILGLLKGL
Physicochemical Analysis
1210.55 Da
8.75
0.76
0.55
0.0633
1.85
0.38
0.66
20.04
227.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.67
-0.54
15.0
15.0
42.0
85.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0359993 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent WO 2020/061306 A1 Evidence URLhttps://patents.google.com/patent/WO2020061306A1/en PatentWO 2020/061306 A1
RECORD: Rec_0362673 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ML-35
PMID23836163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23836163/
RECORD: Rec_0366792 VERIFIED: NO
Provenance & Taxonomy
Social wasp [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0368091 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. parapsilosis ATCC 22019
256 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0379546 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes pallipes [Animal]
MCD; Protonectin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hemolytic
Escherichia coli (Gram-negative)
PMID15052574;15225564;23836163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15052574/
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