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MYP_034408
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Basic Information
Protonectin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C58H107N13O14
Standard
Sequence
ILGTILGLLKGL
Physicochemical Analysis
1210.55 Da
8.75
0.76
0.55
0.0633
1.85
0.38
0.66
20.04
227.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.67
-0.54
15.0
15.0
42.0
85.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0334462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. albicans14-2
128 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0336840 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
3.1 μg/mL
MIC
PMID15225564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15225564/
RECORD: Rec_0339011 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 23857
4 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
RECORD: Rec_0345120 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
rat red blood cell
PMID15225564;15052574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15225564/
RECORD: Rec_0354322 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 14053
16 μM
MIC
PMID28299840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28299840/
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